ABSTRACT
To document number and pattern of neonatal mortality at neonatal Unit. Descriptive Study. The study was conducted in the neonatal Unit of Allied Hospital Faisalabad from 1[st] January 2008 to 31[st] December 2008. The data of all admitted patients during the study period were reviewed and analyzed for age, sex, weight, cause of admission and outcome. A total of 3082 patients were admitted. Among them 58% were male and 42% were female. Most of the patients were admitted in 1[st] 24 hours of life. Major causes of death were birth asphyxia 38%, neonatal infections 29% and prematurity 27%. Birth asphyxia, neonatal infections and prematurity are leading causes of neonatal mortality
ABSTRACT
Objective: To determine the effectiveness of I/V immunoglobulins for prophylaxis against sepsis in preterm newborn. Design of study: Prospective study Setting: Department of Pediatrics at Allied Hospital, Faisalabad. Period: From October 1999 to August 2001
Material and Methods: Seventy newborns of either sex, weighing 1000 gms to 2000 gms [mean 1450 gms] with gestational age 28 to 35 weeks [mean 31 weeks] were included and assigned into 2 groups [35 babies in each group]. On alternate basis one group [study group] was given I/V immunoglobulins 500 mg/kg on day 1, 3 and 10 and the other was not [control group]. The serum level of Immunoglobulins was not determined
Results: Maternal and neonatal risk factors for infection did not differ between the two groups. There was a significant difference in development of sepsis [both culture positive and negative] as well as mortality in the study group as compared to control group. The drug was well tolerated without any significant adverse reactions
Conclusion: It is recommended to give intravenous immunoglobulins to preterm babies, for prophylaxis against infections especially in high risk group